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. Author manuscript; available in PMC: 2010 Dec 3.
Published in final edited form as: DNA Repair (Amst). 2009 Sep 26;8(12):1355–1362. doi: 10.1016/j.dnarep.2009.09.003

Figure 7. Spontaneous mutagenesis and mutation spectra in Polh−/− mice.

Figure 7

The spontaneous mutation frequency was not enhanced in the (A) kidney or liver of 12-month-old Polh−/− mice relative to that in Polk+/+ animals (N=4–7). The mutation spectra in the (B) liver or (C) kidney of Polh−/− mice were also comparable to those observed in Polk+/+ animals.