Table III.
Correlation between left inferior frontal gyrus (x = −48, y = 28, z = 12) and all area in semantic condition
| Regions | BA | Control subjects | Schizophrenia subjects | Control–Schizophrenia subjects | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cluster size | Peak voxel coordinate | No. of subjects (N/10)a | Cluster size | Peak voxel coordinate | No. of Subjects (N/10)a | Cluster size | Peak voxel coordinate | Fisher's Exact testb | ||||||||||
| x | y | z | x | y | Z | x | y | z | χ2 | df | P | |||||||
| L. IFG | 44, 45 | 5,190 | −44 | 22 | 14 | 10 | 2,102 | −46 | 28 | 9 | 10 | ‐ | — | — | ||||
| R. IFG, triangularis | 46, 47 | 4,370 | 44 | 26 | 18 | 10 | 7 | 2,544 | 50 | 20 | 2 | 3.53 | 1 | .21 | ||||
| Bilateral superior Frontal/paracingulate G | 6, 8 | 3,093 | −2 | 30 | 40 | 10 | 578 | 0 | 40 | 42 | 9 | 2,690 | 0 | 26 | 44 | 1.05 | 1 | 1.00 |
| Bilateral precentral G. | 6 | 236 | 4 | −18 | 56 | 6 | 1 | 655 | 8 | −28 | 62 | 5.50 | 1 | .06 | ||||
| L. supeior parietal lobule/intraparietal sulcus/supramarginal G. | 2, 40 | 752 | −40 | −50 | 46 | 10 | 5 | 674 | −30 | −44 | 56 | 6.67 | 1 | .03 | ||||
| R. superior parietal lobule | 40 | 669 | 36 | −50 | 46 | 9 | 5 | 408 | 32 | −58 | 42 | 3.81 | 1 | 0.14 | ||||
| L. superior temporal sulcus/middle temporal G. | 21 | 75 | −56 | −34 | −4 | 8 | 3 | 67 | −60 | −38 | −2 | 7.50 | 1 | 0.02 | ||||
| L. globus pallidus | 185 | −20 | −10 | −2 | 9 | 4 | 137 | −24 | −8 | −4 | 5.50 | 1 | 0.06 | |||||
| L. thalamus | 133 | −10 | −20 | 2 | 9 | 4 | 94 | −8 | −16 | 2 | 5.50 | 1 | 0.06 | |||||
| L. cuneus | 17, 30 | 972 | 4 | −70 | 8 | 2.22 | 1 | 0.48 | ||||||||||
| L. cerebellum | 1,787 | −22 | −70 | −24 | 10 | 7 | 1,191 | −16 | −68 | 16 | 3.53 | 1 | 0.21 | |||||
| R. cerebellum | 1,519 | 32 | −64 | −22 | 10 | 6 | 1,223 | 24 | −72 | −24 | 5.00 | 1 | 0.09 | |||||
Notes: No suprathreshold regions identified for the contrast of Schizophrenia subjects – Control subjects. BA = Brodman's area, L = left, R = right, G = gyrus, IFG = inferior frontal gyrus.
Statistical significance was confirmed through analysis of 5,000 nonparametric permutations. Activations identified at cluster‐level significance of P < 0.05 for a spatial extent of at least 50 voxels for both within and between group analysis. The effect of verbal IQ was removed for the between group analysis.
No. of Subjects: the number of subjects showing true correlation which was defined as a correlation coefficient greater than 0.374 which matched the 99.99 percentile rank of the noise distribution, at each region of interest.
Fisher's Exact test: group comparison test of No. of Subjects showing true correlation.