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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Clin Cancer Res. 2009 Nov 24;15(23):7316–7321. doi: 10.1158/1078-0432.CCR-09-1263

Table 1.

Expectant Management Cohort Patients Characteristics at Diagnosis

Variable Favorable (N = 32) Unfavorable (N = 39) p value*
Mean ± SD [Median] Mean ± SD [Median]
Age 65.42 ± 4.37 [65.03] 64.82 ± 4.70 [64.97] 0.991
tPSA (ng/ml) 4.61 ± 2.75 [4.36] 5.35 ± 2.02 [5.53] 0.056
fPSA (ng/ml) 0.88 ± 0.59 [0.74] 0.97 ± 0.52 [0.89] 0.298
%fPSA 19.15 ± 6.36 [18.98] 18.40 ± 6.44 [18.21] 0.587
[−2] proPSA (pg/ml) 12.21 ± 7.43 [11.36] 15.00 ± 6.97 [14.24] 0.051
[−2] proPSA/%fPSA 0.65 ± 0.36 [0.55] 0.87 ± 0.44 [0.88] 0.018
PSAD (ng/ml/cm3) 0.094 ± 0.058 [0.087] 0.100 ± 0.0369 [0.100] 0.173
Prostate Volume 51.86 ± 17.50 [50.00] 57.29 ± 29.27 [50.00] 0.737
Number of Positive Core 1.19 ± 0.40 [1.00] 1.18 ± 0.39 [1.00] 0.931
Maximum %core involvement with Cancer 7.39 ± 10.13 [1.00] 8.29 ± 11.60 [1.00] 0.741
Cancer IHC
[−5/−7] proPSA %Area 11.87 ± 9.67 [9.51] 13.70 ± 9.62 [12.90] 0.371
[−5/−7] proPSA Stain Intensity 4552.54 ± 2923.61 [4055.18] 4611.47 ± 3293.73 [3119.32] 0.786
Benign Adjacent Area IHC
[−5/−7] proPSA %Area 6.88 ± 5.20 [5.38] 11.58 ± 7.08 [10.14] 0.009
[−5/−7] proPSA Stain Intensity 2418.06 ± 1606.04 [1819.76] 4104.09 ± 3033.50 [3196.52] 0.025

For Cancer and Benign Adjacent Area IHC number of subjects (favorable/unfavorable) were 57 (27/30) and 54 (25/29) respectively

*

p values calculated using Mann-Whitney test.