Table 1.
Variable | Favorable (N = 32) | Unfavorable (N = 39) | p value* |
---|---|---|---|
Mean ± SD [Median] | Mean ± SD [Median] | ||
Age | 65.42 ± 4.37 [65.03] | 64.82 ± 4.70 [64.97] | 0.991 |
tPSA (ng/ml) | 4.61 ± 2.75 [4.36] | 5.35 ± 2.02 [5.53] | 0.056 |
fPSA (ng/ml) | 0.88 ± 0.59 [0.74] | 0.97 ± 0.52 [0.89] | 0.298 |
%fPSA | 19.15 ± 6.36 [18.98] | 18.40 ± 6.44 [18.21] | 0.587 |
[−2] proPSA (pg/ml) | 12.21 ± 7.43 [11.36] | 15.00 ± 6.97 [14.24] | 0.051 |
[−2] proPSA/%fPSA | 0.65 ± 0.36 [0.55] | 0.87 ± 0.44 [0.88] | 0.018 |
PSAD (ng/ml/cm3) | 0.094 ± 0.058 [0.087] | 0.100 ± 0.0369 [0.100] | 0.173 |
Prostate Volume | 51.86 ± 17.50 [50.00] | 57.29 ± 29.27 [50.00] | 0.737 |
Number of Positive Core | 1.19 ± 0.40 [1.00] | 1.18 ± 0.39 [1.00] | 0.931 |
Maximum %core involvement with Cancer | 7.39 ± 10.13 [1.00] | 8.29 ± 11.60 [1.00] | 0.741 |
Cancer IHC† | |||
[−5/−7] proPSA %Area | 11.87 ± 9.67 [9.51] | 13.70 ± 9.62 [12.90] | 0.371 |
[−5/−7] proPSA Stain Intensity | 4552.54 ± 2923.61 [4055.18] | 4611.47 ± 3293.73 [3119.32] | 0.786 |
Benign Adjacent Area IHC† | |||
[−5/−7] proPSA %Area | 6.88 ± 5.20 [5.38] | 11.58 ± 7.08 [10.14] | 0.009 |
[−5/−7] proPSA Stain Intensity | 2418.06 ± 1606.04 [1819.76] | 4104.09 ± 3033.50 [3196.52] | 0.025 |
For Cancer and Benign Adjacent Area IHC number of subjects (favorable/unfavorable) were 57 (27/30) and 54 (25/29) respectively
p values calculated using Mann-Whitney test.