. Author manuscript; available in PMC: 2010 Dec 1.

Published in final edited form as: Exp Gerontol. 2009 Oct 9;44(12):799–804. doi: 10.1016/j.exger.2009.10.002

Table 3.

Associations between baseline or 5-year change in biomarker^a and 3-year change in physical functioning measures

	_LogCRP		_LogFibrinogen

	Baseline	5-year change	Baseline	5-year change
Three-year change in independent variables	β (SE)	β (SE)	β (SE)	β (SE)
Grip strength, dominant hand (kg)	−0.18 (0.1)	−0.42 (0.2)^b	0.30 (0.8)	−0.13 (0.9)
_LogTime in double support (%)	0.01 (0.005)^c	−0.004 (0.007)	0.12 (0.05)^b	0.09 (0.06)
Forward reach (cm)	−0.45 (0.2)^c	−0.05 (0.3)	0.49 (1.1)	0.60 (1.3)
_Log2-lb lift (seconds)	0.005 (0.008)	0.018 (0.01)	0.03 (0.06)	0.11 (0.07)
_LogChair rise (seconds)	0.02 (0.01)	0.007 (0.02)	−0.001 (0.07)	−0.02 (0.09)
_Log40-foot timed walk (seconds)	0.01 (0.006)	0.008 (0.009)	0.04 (0.04)	0.02 (0.05)
_LogTimed stair climb (seconds)	0.002 (0.004)	0.01 (0.006)	0.08 (0.04)^b	0.12 (0.04)^c

Two models were run for each outcome including either baseline and change in _logCRP or baseline and change in _logfibrinogen. Models were all adjusted for the initial value of the dependent variable. Models were also adjusted for age, race/ ethnicity, economic stress, smoking, heart disease, arthritis, high blood pressure, diabetes and BMI as appropriate.

p≤0.05

p≤0.01

p≤0.0001