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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Clin Cancer Res. 2009 Nov 17;15(23):7299–7308. doi: 10.1158/1078-0432.CCR-09-1745

Figure 5.

Figure 5

In-vivo assessment of apoptotic efficacy of various treatments in H1299 lung cancer xenografts in mice. Representative photomicrographs of apoptotic cells in A) intravenous and B) intratumoral groups using TUNEL assay in one representative section out of n = 6 xenografts. C) The apoptotic index following intravenous and intratumoral treatments with docetaxel, D-D, Flt23k-NP, RGD-Flt23k-NP, D-D + RGD-Flt23k-NP. The arrows indicate some TUNEL positive cells in a field. Data are expressed as mean ± standard deviation for n = 6. D) Representative photomicrographs of apoptosis in proliferative endothelial cells using a dual CD31 and TUNEL staining in one representative section out of 6 xenografts.