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In-vivo assessment of efficacy of various treatment groups in inhibiting VEGF expression in H1299 lung cancer xenografts models. Representative photomicrographs of VEGF expression (brown stain) using a VEGF immunohistochemistry assay in A) intravenous and B) intratumoral groups following various treatments including docetaxel, D-D, Flt23k-NP, RGD-Flt23k-NP, and D-D + RGD-Flt23k-NP. These are representative of sections in one out of 6 xenografts.
