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. Author manuscript; available in PMC: 2010 Dec 16.
Published in final edited form as: J Control Release. 2009 Jun 7;140(3):301–305. doi: 10.1016/j.jconrel.2009.05.035

Figure 1. Binding of plasma proteins to iron oxide nanoparticles.

Figure 1

The nanoparticles were incubated with plasma or peptides as described in Methods. Particle-bound proteins were eluted and separated by SDS gel electrophoresis. The proteins were analyzed with specific antibodies against kininogen and kallikrein. Both antibodies were specific for the light chain of the proteins, detecting uncleaved 120 kDa kininogen and 88kDa kallikrein (arrows), or the cleaved light chain of both proteins (between 50 and 64 kDa size). One representative experiment out of 5 is shown.