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. Author manuscript; available in PMC: 2010 Dec 16.
Published in final edited form as: J Control Release. 2009 Jun 7;140(3):301–305. doi: 10.1016/j.jconrel.2009.05.035

Figure 2. Kallikrein activation in human and mouse plasma.

Figure 2

Nanoparticles were incubated with diluted citrated plasma and with kallikrein chromogenic substrate as described in Methods. A, Effect of SPIONs on kallikrein activation in normal and kininogen-deficient mouse plasma; B, Kallikrein activity in human plasma and the role of Factor XII deficiency in the activation. The experiments were repeated 3 times.