. Author manuscript; available in PMC: 2009 Dec 3.

Published in final edited form as: Int J Geriatr Psychiatry. 2009 Dec;24(12):1335–1342. doi: 10.1002/gps.2263

Table 3.

Summary of results from comparative studies

	Sinoff and Werner, 2003	Palmer et al., 2007	Devier, current study
Sample type	Clinic based study	Population based study	Clinic based study
Sample size	42 anxiety, no cognitive impairment; 58 controls	47 patients with MCI; 185 controls	148 cognitive impairment (108 amnestic MCI +/−; 20 non-amnestic MCI, 20 no MCI) 63 controls
Age mean (SD)	Patients: 75.9 (5.0) Controls: 78.9 (6.3)	Entire sample: 84.0 (5.1)	Patients: 67.1 (9.9) Controls: 65.7 (9.3)
Cognitive inclusion	No cognitive impairment	Patients with MCI	Patients with cognitive impairment
MMSE	MMSE ≥ 24	Patients: MMSE < 24 Controls: MMSE > 24	Patients: MMSE ≥ 22 Controls: MMSE ≥ 27
Anxiety scales	Sinoff’s Short Anxiety Screening Test	Comprehensive Psychopatho- logical Rating Scale	STAI
State/Trait	State	State	State and Trait
Average follow-up duration	3.1 years	3.4 years	4.3 years evaluated annually
Findings	Anxiety predicted cognitive decline	Anxiety predicted conversion from MCI to AD	State anxiety did not predict conversion from MCI to AD; Higher Trait anxiety scores predicted a lower risk of conversion from MCI to AD