Table 2.
Secondary screening by AnnexinV/PI staining % conferred reduction compared to vehicle controls is shown. Only the compounds with statistically significant reduction in apoptosis in W-T or A-T LCLs are shown (P < 0.05).
Compound (µM) | W-T | A-T |
---|---|---|
tetracycline (20) | 19 | NS |
norfloxacin (40) | 28 | 28 |
levofloxacin (40) | 16 | 34 |
doxycycline (10) | NS | 31 |
chlorotetracycline (20) | NS | 48 |
moxifloxacin (10) | NS | 50 |
ciprofloxacin (5) | 21 | NS |
flumequine (100) | 25 | 37 |
enoxacin (100) | 18 | NS |
5’-AMP (20) | 34 | 13 |
NS=not significant