Table 5.
Sensitivity and Specificity of Diagnostic Parameters
| Threshold | 5th percentile | 1st percentile | ||||
|---|---|---|---|---|---|---|
| parameter | Sensitivity (PG) |
Sensitivity (PPG) |
Specificity | Sensitivity (PG) |
Sensitivity (PPG) |
Specificity |
| RTVue FD-OCT | ||||||
| GCC-AVG | 0.61 (0.05) | 0.34 (0.06) | 0.95 (0.02) | 0.43 (0.05) | 0.13 (0.04) | 0.99 (0.01) |
| GCC-FLV | 0.72 (0.05) | 0.30 (0.05) | 0.95 (0.02) | 0.36 (0.05) | 0.04 (0.03) | 0.99 (0.01) |
| GCC-GLV | 0.63 (0.06) | 0.33 (0.06) | 0.95 (0.02) | 0.46 (0.05) | 0.11 (0.03) | 0.98 (0.01) |
| GCC-PCV | 0.6 (0.05) | 0.17 (0.05) | 0.97 (0.02) | 0.41 (0.05) | 0.05 (0.03) | 0.98 (0.01) |
| GCC-SID | 0.28 (0.04) | 0.09 (0.04) | 0.94 (0.02) | 0.16 (0.04) | 0.94 (0.02) | 0.99 (0.01) |
| MR-AVG | 0.36 (0.05) | 0.2 (0.06) | 0.97 (0.02) | 0.14 (0.04) | 0.01 (0.01) | 1 (0) |
| Stratus TD-OCT | ||||||
| NFL-AVG | 0.75 (0.04) | 0.39 (0.06) | 0.97 (0.02) | 0.6 (0.05) | 0.3 (0.06) | 0.98 (0.02) |
| MR-AVG | 0.37 (0.05) | 0.26 (0.06) | 0.97 (0.02) | 0.21 (0.05) | 0.05 (0.03) | 0.99 (0.01) |
Abbreviation: PPG = pre-perimetric glaucoma; PG = perimetric glaucoma; GCC = ganglion ceil complex thickness; AVG = average; FLV (%) = focal loss volume expressed as a percentage of the average GCC volume in the normal group; GLV = global loss volume; PCV = pattern coefficient of variation; SID = superior - inferior difference; MR = macular retina thickness; NFL = nerve fiber layer thickness; FD-OCT: Fourier-domain optical coherence tomography; TD-OCT: time-domain optical coherence tomography