Table 2.
Effects of VDIS Intervention on Laboratory Outcomes at Censoring
| Outcome | Control | Intervention | Unadjusted effecta | Adjusted effect (CI)b | Pb |
|---|---|---|---|---|---|
| On-time testing (complete data; n = 7,412) | |||||
| A1C | 55% | 56% | OR = 1.06 | 1.17 (0.80, 1.72) | 0.43 |
| Lipids | 71% | 74% | OR = 1.17 | 1.39 (1.08, 1.80) | 0.012 |
| Creatinine | 80% | 84% | OR = 1.26 | 1.40 (1.06, 1.84) | 0.018 |
| Urine protein | 32% | 40% | OR = 1.41 | 1.74 (1.13, 2.69) | 0.012 |
| Physiologic control (non-imputed; n = 4,998 for A1C; n = 5,450 for LDL) | |||||
| Mean A1C (%) | 7.01 | 7.16 | AD = +0.16 | +0.12 (−0.01, +0.25) | 0.08 |
| Mean LDL (mg/dl) | 93.4 | 93.5 | AD = −0.1 | +0.4 (−2.2, +3.1) | 0.74 |
| A1C <7% | 59% | 54% | OR = 0.82 | 0.84 (0.66, 1.08) | 0.18 |
| LDL <100 mg/dl | 63% | 64% | OR = 1.04 | 1.04 (0.87, 1.23) | 0.68 |
| Physiologic control (imputed data; n = 7,412) | |||||
| Mean A1C (%) | 7.10 | 7.25 | AD = +0.15 | +0.10 (−0.05, +0.24) | 0.17 |
| Mean LDL (mg/dl) | 95.8 | 95.0 | AD = −0.8 | +0.2 (−2.5, +3.0) | 0.86 |
| A1C <7% | 59% | 54% | OR = 0.82 | 0.84 (0.66, 1.08) | 0.18 |
| LDL <100 mg/dl | 63% | 64% | OR = 1.07 | 1.04 (0.88, 1.23) | 0.65 |
aOR = odds ratio; AD = absolute difference (Intervention–Control)
bLogistic or linear regression adjusted for baseline patient value, baseline practice performance, and clustering within practices, with 95% confidence intervals