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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Dev Biol. 2009 Oct 20;337(1):124–133. doi: 10.1016/j.ydbio.2009.10.021

Figure 5.

Figure 5

Inhibition of mast cell degranulation blocked normal mammary gland branching. Mice were treated with cromolyn sodium, a mast cell degranulation inhibitor, or control from weeks 3 to 5 of age (n=7 mice/group). A) Carmine-stained whole mounts of saline- and cromolyn sodium-treated mammary glands at 5 weeks. Scale bar = 1 mm. The edge of mammary gland growth is outlined in white. B) Cromolyn sodium-treated mammary glands have fewer TEBs after two weeks of treatment (Student's t-test: **P=0.0047). C) Cromolyn sodium-treated mammary glands have fewer invading duct ends after two weeks of treatment (Student's t-test: *P=0.049). All error bars represent standard deviation.