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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Dev Biol. 2009 Oct 20;337(1):124–133. doi: 10.1016/j.ydbio.2009.10.021

Figure 6.

Figure 6

Mammary gland development is defective in mice lacking normal mast cell protease activation. Mammary glands of DPPI-/- mice and wild-type controls at 5 and 8 weeks of age were examined in whole mount preparations (n=6 mice/group). A) Carmine-stained whole mounts of wild-type and DPPI-/- mammary glands at 5 and 8 weeks. Scale bar = 1 mm. The edge of mammary gland growth is outlined in white. B) Mammary glands of DPPI-/- mice have fewer TEBs than wild-type controls at both 5 and 8 weeks of age (Student's t-test: *5 weeks, P<0.0001; **8 weeks, P=0.0013). C) Mammary glands of DPPI-/- mice have fewer duct ends than wild-type controls as both 5 and 8 weeks of age (Student's t-test: *5 weeks, P=0.0015; **8 weeks, P=0.0006). All error bars represent standard deviation.