Figure 2. Anti-VacV neutralizing antibody kinetics.
VacV neutralizing antibody titers (PRNT50) from intact serum sample (closed circles) and IgM depleted serum samples (open squares) were determined by testing daily serum samples after VacV infection. N = 4/group. Total vs IgM depleted samples at day 4 post-infection, P = 0.0153. **, P < 0.01. *, P < 0.05. Error bars represent SEM. Dotted line indicates LOD. Data is representative of 2 independent time course experiments.