Table 3.
Reappraise Negative Self-Beliefs Early versus Late BOLD Responses in Patients with Social Anxiety Disorder versus Healthy Controls froi 40
Brain Region | BA | Peak x y z |
Vol mm3 |
t-value |
---|---|---|---|---|
Early > Late | ||||
HC > SAD | ||||
Frontal Cortex | ||||
R Inferior Frontal Gyrus | 45, 47 | 55 21 −2 | 5860 | 3.74 |
Dorsomedial PFC | 6, 8 | 0 21 63 | 4640 | 3.12 |
L Ventrolateral PFC | 10 | −34 62 −9 | 4396 | 2.99 |
Dorsal Cingulate Gyrus | 24, 23 | −3 −10 32 | 100 | 4.17 |
Dorsal Anterior Cingulate Cortex | 24 | 3 14 29 | 4070 | 3.98 |
L Inferior Frontal Gyrus | 47 | −34 28 −2 | 1221 | 4.39 |
L Dorsolateral PFC | 9 | −48 7 36 | 1221 | 2.97 |
R Dorsolateral PFC | 9 | 48 18 36 | 7733 | 3.45 |
Medial Anterior PFC | 10, 9 | −3 62 36 | 407 | 3.24 |
Medial Anterior PFC | 10 | 14 62 19 | 285 | 3.36 |
R Dorsolateral PFC | 45, 46 | 52 25 22 | 285 | 3.22 |
Temporal Lobe | ||||
L Superior Temporal Gyrus | 22, 21 | −69 −13 8 | 488 | 3.52 |
L Posterior Middle Temporal Gyrus | 19 | −31 −75 22 | 285 | 4.13 |
R Inferior Temporal Gyrus | 20 | 55 −34 −16 | 244 | 3.84 |
Parietal Cortex | ||||
R Supramarginal Gyrus, | 39, 40 | 55 −58 32 | 2564 | 3.51 |
R Inferior Parietal Lobule | ||||
Medial Precuneus | 7 | −3 −68 43 | 1302 | 3.01 |
L Superior Parietal Lobule, | 7 | −38 −65 53 | 814 | 3.50 |
L Inferior Parietal Lobule | ||||
R Inferior Parietal Lobule | 40 | 48 −58 46 | 488 | 4.34 |
Subcortical | ||||
L Thalamus | −7 −10 −2 | 529 | 3.37 | |
L Thalamus | −14 −20 −2 | 285 | 3.59 | |
Late > Early | ||||
SAD > HC | ||||
Frontal Cortex | ||||
R Dorsolateral PFC | 8, 9, 6 | 48 11 39 | 1262 | 3.18 |
R Ventrolateral PFC | 10 | 28 69 12 | 4233 | 4.62 |
L Dorsolateral PFC | 46, 10 | −41 38 26 | 692 | 3.64 |
R Dorsolateral PFC | 6 | 17 28 56 | 570 | 2.97 |
R Dorsolateral PFC | 9 | 41 38 32 | 488 | 3.16 |
L Insula | 13 | −41 7 8 | 611 | 3.51 |
L Anterior Insula | 13 | −31 18 8 | 163 | 3.58 |
R Insula | 13 | 38 4 −2 | 570 | 3.49 |
R Posterior Insula | 13 | 34 −17 19 | 529 | 3.23 |
L Precentral Gyrus | 4 | −65 1 22 | 163 | 3.25 |
Parietal Lobe | ||||
L Inferior Parietal Lobule | 40 | −58 −31 32 | 1180 | 2.94 |
L Inferior Parietal Lobule | 40 | −58 −48 39 | 163 | 3.20 |
R Precuneus | 7 | 10 −58 36 | 977 | 4.15 |
L Precuneus | 7 | −10 −37 50 | 448 | 3.62 |
Temporal Lobe | ||||
R Superior Temporal Gyrus | 22 | 55 −6 5 | 326 | 3.53 |
Subcortical | ||||
R Thalamus | 7 −10 12 | 1913 | 3.54 | |
L Thalamus | −10 −13 12 | 326 | 3.39 | |
R Lentiform Nucleus, Putamen | 17 4 −5 | 285 | 3.09 |
Note. Between-group t-test, t>2.932, voxel P<.005, cluster volume>162mm3, cluster P<.01 BA=Brodmann Areas, HC=healthy controls, L=left, PFC=prefrontal cortex, R=right, SAD=patients with social anxiety disorder.