Skip to main content
. 2009 Aug 11;17(12):2088–2095. doi: 10.1038/mt.2009.184

Figure 3.

Figure 3

Enhanced transduction of primary human astrocytes by novel AAV variants. (a) Transduction of primary human astrocytes by rAAV CMV-GFP vectors with capsids selected from the AAV EP, chimera, and random loop libraries demonstrated enhanced gene delivery by numerous viral variants (n = 3, error bars represent SD). (b) Transduction of SHSY-5Y neuroblastoma cells with rAAV CMV-GFP vectors revealed a decrease in transduction for most EP, chimera, and random loop variants, except for L1-12 (n = 3, error bars represent SD). AAV, adeno-associated virus; CMV, cytomegalovirus; GFP, green fluorescent protein.