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. Author manuscript; available in PMC: 2010 Dec 7.
Published in final edited form as: J Org Chem. 2009 Dec 4;74(23):8997–9009. doi: 10.1021/jo901641k

SCHEME 2.

SCHEME 2

Synthesis of maleimide pyridocarbazole 7. a Reaction conditions: First, 1.1 equiv of 8, 1.0 equiv 9, 0.1 equiv of Pd(0) catalyst, 2.75 equiv Na2CO3, DME/H2O, reflux, overnight, then 10:1 mass ratio silica gel:indole, high vacuum, 80 °C, overnight.