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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Placenta. 2009 Nov 5;30(12):1045–1051. doi: 10.1016/j.placenta.2009.10.007

Figure 5.

Figure 5

Effects of PD98059 and U0126 on FGF2- and VEGF-stimulated HPAE cell proliferation. Cells were cultured under normoxia for 24 hr. After 24 hr of serum starvation, cells seeded in 96-well plates were treated with 10 ng/ml of FGF2 (A and C) or VEGF (B and D) in the absence or presence of PD98059 (2.5–40 μM) or U0126 (0.625–10μM; 1 hr pretreatment). Cells were counted after 72 hr of treatment. Data are expressed as means ± SEM percentage of the control (n = 4). The number of cells per well in the control was 6029 ± 457.4 and 4407 ± 139.6, respectively, for the PD98059 (A and B) and U0126 (C and D) treatments. a,b,c Means with different letters differ within each growth factor and kinase inhibitor treatment (p < 0.05).