Table 1. Percentage CpG methylation in the proximal promoter of the mature EC marker VE-cadherin and the EC differentiation inducers BMP4, VEGF-A and EPAS-1.
Number of CG sites* | ESC | ESC+Vehicle | ESC +aza-dC | mBEC | |
---|---|---|---|---|---|
VE-cadherin | 14 | 100 | 98 | 90 | 94 |
BMP4 | 10 | 9 | 15 | 17 | 11 |
EPAS-1 | 7 | 0 | nd | nd | nd |
VEGF-A | 42 | 4 | nd | 2 | 2 |
The number of CG sites analyzed for each gene are indicated. Ten clones were analyzed for each CG site. The data is the average percentage methylation over all CpG sites analyzed.