Table II.
Distributions of Polymorphic Alleles at the Genotyped Tag SNP Sites in STAT3 and TYK2 Among Study Subjects
| Gene | SNP | Allele | Number (%) of alleles in | Allele comparisona | Number (%) of alleles in | Allele comparisona | ||
|---|---|---|---|---|---|---|---|---|
| UC | Control | P value | CD | Control | P value | |||
| STAT3 | rs8074524 | C | 144 (64.3) | 253 (63.3) | 0.759 | 106 (63.9) | 253 (63.3) | 0.892 |
| T | 80 (35.7) | 147 (36.7) | 60 (36.1) | 147 (36.7) | ||||
| rs2293152 | G | 151 (66.2) | 267 (66.7) | 0.894 | 91 (54.8) | 267 (66.7) | 0.007 | |
| C | 77 (33.8) | 133 (33.3) | 75 (45.2) | 133 (33.3) | ||||
| rs957970 | A | 116 (51.8) | 218 (54.5) | 0.652 | 84 (50.6) | 218 (54.5) | 0.397 | |
| G | 108 (48.2) | 182 (45.5) | 82 (49.4) | 182 (45.5) | ||||
| TYK2 | rs280496 | C | 201 (89.7) | 362 (90.5) | 0.784 | 144 (86.7) | 362 (90.5) | 0.187 |
| G | 23 (10.3) | 38 (9.5) | 22 (13.3) | 38 (9.5) | ||||
| rs280519 | A | 136 (60.7) | 224 (56.0) | 0.261 | 109 (65.7) | 224 (56.0) | 0.034 | |
| G | 88 (39.3) | 176 (44.0) | 57 (34.3) | 176 (44.0) | ||||
| rs2304256 | C | 156 (69.6) | 262 (65.5) | 0.311 | 129 (77.7) | 262 (65.5) | 0.004 | |
| A | 68 (30.4) | 138 (34.5) | 37 (23.3) | 138 (34.5) | ||||
| rs280523 | G | 207 (92.4) | 370 (92.5) | 0.968 | 154 (92.8) | 370 (92.5) | 0.911 | |
| A | 17 (7.6) | 30 (7.5) | 12 (7.2) | 30 (7.5) | ||||
| Total number of alleles | 228 | 400 | 166 | 400 | ||||
aEach allele was compared to another allele using a chi-square test.