Table IV.
Distributions of Haplotypes of TYK2 Between CD Patients and Control Subjects
| Haplotype | SNP | Number (%) of haplotypes in | Haplotype comparisona | |||
|---|---|---|---|---|---|---|
| rs280519 | rs2304256 | CD | Control | OR (95% CI) | P value | |
| Hap 1 | A | C | 109 (65.7) | 221 (55.3) | 1.549 (1.063–2.256) | 0.023 |
| Hap 2 | G | A | 37 (22.3) | 135 (33.7) | 0.563 (0.370–0.857) | 0.007 |
| Hap 3 | G | C | 20 (12.0) | 41 (10.3) | 1.199 (0.680–2.117) | 0.530 |
| Hap 4 | A | A | 0 | 3 (0.7) | – | – |
| Total number of haplotypes | 166 | 400 | ||||
OR odds ratio, CI confidence interval
aEach haplotype was compared to other haplotypes combined using a logistic regression analysis