Table V.
Distributions of Diplotypes of TYK2 Between CD Patients and Control Subjects
| Diplotype | Number (%) of diplotypes in | Diplotype comparisona | ||
|---|---|---|---|---|
| CD | Control | OR (95% CI) | P value | |
| Hap 1/Hap 1 | 37 (44.6) | 61 (30.5) | 1.833 (1.082–3.105) | 0.024 |
| Hap 1/Hap 2 | 20 (24.1) | 73 (36.5) | 0.552 (0.309–0.986) | 0.045 |
| Hap 1/Hap 3 | 15 (18.1) | 24 (12.0) | 1.618 (0.801–3.268) | 0.180 |
| Hap 1/Hap 4 | 0 | 2 (1.0) | – | – |
| Hap 2/Hap 2 | 6 (7.2) | 23 (11.5) | 0.600 (0.235–1.531) | 0.285 |
| Hap 2/Hap 3 | 5 (6.0) | 15 (7.5) | 0.791 (0.278–2.251) | 0.660 |
| Hap 2/Hap 4 | 0 | 1 (0.5) | – | – |
| Hap 3/Hap 3 | 0 | 1 (0.5) | – | – |
| Total number | 83 | 200 | ||
OR odds ratio, CI confidence interval
aEach diplotype was compared to other diplotypes combined using a logistic regression analysis