Table I.
Total number of B cells sorted by donor group and yield of single B cell-derived cultures secreting human immunoglobulin (Ig) or RSV F-specific antibodies.
Donor group | Number of subjects |
Number of wells sorted |
Number secreting human Ig (%) |
Number secreting RSV F- specific antibodies (%) |
---|---|---|---|---|
Adult blood donors | 9 | 11,927 | 2,732 (21) | 193 (7) |
RSV-infected adults | 12 | 3,691 | 401 (26) | 21 (5) |
RSV-infected children (≥3 months) |
9 | 6,290 | 1,347 (21) | 91 (7) |
RSV-infected infants (< 3 months) |
12 | 14,664 | 3,295 (22) | 146 (5) |
Total | 42 | 36,572 | 7,775 (21) | 451 (6) |