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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Clin Cancer Res. 2009 Nov 17;15(23):7381–7388. doi: 10.1158/1078-0432.CCR-09-1735

Fig 1.

Fig 1

FISH was performed to assess HER2 status. (A) FISH performed on biopsy specimen prior to treatment with a trastuzumab containing neoadjuvant chemotherapy regimen. Red = HER2 gene, green = centromere of chromosome 17 (CEP17). HER2/CEP17 = 6.22. Due to the intensity of HER2 staining, merged images were not obtained. (B) FISH performed on residual disease identified at the time of surgery from the same patient following completion of neoadjuvant chemotherapy. Image shown is a merged image of staining for HER2 and CEP 17. HER2/CEP17 = 1.1.