Table 4.
Kaplan-Meier Estimates of RFS Among All Patients by pCR and by HER2 Status in Patients with Residual Tissue Identified at the Time of Surgery
| Status | No. of Patients | No. of Events | Median Follow-Up | 3 - Year Estimates | 5 - Year Estimates | p-value | ||
|---|---|---|---|---|---|---|---|---|
| Time (months) | % | 95% CI | % | 95% CI | ||||
| Overall | 142 | 17 | 33.5 | 87.8 | 82.4 to 93.6 | 86.20 | 80.1 to 92.8 | |
| pCR | 33.5 | |||||||
| Yes | 72 | 4 | 95.7 | 91.0 to 100 | 92.90 | 86.0 to 100 | ||
| No | 70 | 13 | 80.1 | 70.8 to 90.5 | - | 0.0175 | ||
| HER2 Status in Residual Tissue | 25 | 6 | 37.0 | 74.9 | 59.4 to 94.5 | - | - | |
| Amplified | 17 | 2 | 87.5 | 72.7 to 100 | - | - | ||
| Not Amplified | 8 | 4 | 50.0 | 25.0 to 100 | - | - | 0.041 | |