Table 5.
Comparison of results obtained from calculating risk of any one of four major osteoporotic fractures among postmenopausal white women by either summing rates of four individual types of fracture or by measuring the risk of any one of the four types, comparing data from Malmo, Sweden, with prospective data from the Study of Osteoporotic Fractures (SOF)
| Malmo 10-year risk [32] | SOF 10-year riska | ||||||
|---|---|---|---|---|---|---|---|
| Age | Any of 4 | Sum of 4 | Ratio of “any” to sum (and implied discount to sum) | Age | Any of 4 | Sum of 4 | Ratio of “any” to sum (and implied discount to sum) |
| 50 | 6.0 | 6.9 | 0.87 (13%) | ||||
| 55 | 7.8 | 9.0 | 0.87 (13%) | ||||
| 60 | 10.6 | 12.9 | 0.82 (18%) | ||||
| 65 | 14.3 | 18.1 | 0.79 (21%) | 65–69 | 12.9 | 14.29 | 0.91 (9%) |
| 70 | 18.9 | 24.8 | 0.76 (24%) | 70–74 | 17.3 | 20.13 | 0.86 (14%) |
| 75 | 22.9 | 30.8 | 0.74 (26%) | 75–79 | 24.24 | 27.54 | 0.88 (12%) |
| 80 | 26.5 | 35.3 | 0.75 (25%) | 80–84 | 26.45 | 32.16 | 0.82 (18%) |
| 85 | 27.0 | 35.2 | 0.77 (24%) | ≥85 | 34.53 | 38.74 | 0.89 (11%) |
| 90 | 21.4 | 27.5 | 0.78 (22%) | ||||
Discount is the estimated decrease in the sum of the four due to overlap in individuals suffering more than one type of fracture
aStudy of Osteoporotic Fractures: unpublished data