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. 2009 Dec 11;4(12):e8249. doi: 10.1371/journal.pone.0008249

Figure 1. Large ribosomal subunit rRNA maturation pathways in S. cerevisiae.

Figure 1

Four of the five rRNAs found in mature ribosomes are derived from transcripts made by RNA polymerase I and processed through a series of endo- and exonucleolytic reactions. In (A) External transcribed spacer regions (ETS1, ETS2), Internal transcribed spacer regions (ITS1, ITS2), the transcription start site (+1) and major rRNA processing sites of primary rDNA transcripts are indicated. In (B) major pathways of precursor rRNA processing are shown.