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. 2009 Nov 24;101(11):1817–1823. doi: 10.1038/sj.bjc.6605428

Table 2. (a–c) The relationship between CYP2C8 and CYP2C9 genotypes in the breast cancer patient group.

(a) CYP2C8*1/*1 CYP2C8*1/*4 CYP2C8*4/*4 n
CYP2C8*1/*1 445 76 3 524
CYP2C8*1/*3 116 5 0 121
CYP2C8*3/*3 7 0 0 7
n 568 81 3 652
         
(b) CYP2C9*1/*1 CYP2C9*1/*3 CYP2C9*3/*3 n
CYP2C9*1/*1 438 67 2 507
CYP2C9*1/*2 124 11 0 135
CYP2C9*2/*2 8 0 0 8
n 570 78 2 650
         
(c) CYP2C9*1/*1 CYP2C9*1/*2 CYP2C9*2/*2 n
CYP2C8*1/*1 498 25 1 524
CYP2C8*1/*3 9 110 1 120
CYP2C8*3/*3 0 1 6 7
n 507 136 8 652

Abbreviation: CYP=cytochrome P450.

Table 2a shows linkage disequilibrium (LD) between the CYP2C8*3 and CYP2C8*4 genotypes among the 652 breast cancer patients included. Table 2b shows LD between the CYP2C9*2 and CYP2C9*3 genotypes. Table 2c confirms the previously reported imperfect LD between CYP2C8*3 and CYP2C9*2. Genotype data on CYP2C9*2 were missing for one woman and CYP2C9*3 genotype data were missing for another woman.