Skip to main content
. 2009 Dec 14;4(12):e8285. doi: 10.1371/journal.pone.0008285

Figure 5. PLCγ1 is necessary for FGF-2-induced tubulogenesis in vitro.

Figure 5

(A) Representative images of HUVEC on Matrigel in the absence or presence of FGF-2 plus 2 µM of the PLC inhibitor U73122 or its inactive analogue U73343. Plot represents a quantitative analysis of the experiments obtained by counting the number of branch points from five fields. Data are means±SEM of values obtained from 12 independent experiments.**p<0.01. NS = not significant. (B) Representative images of HUVEC transfected with the scrambled siRNA or siRNA targeting PLCγ1 on Matrigel in the presence of FGF-2. Quantitative analysis show data as means±SEM of values obtained from 5 independent experiments. NS = not significant.