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. 2009 Sep 16;18(11):2336–2345. doi: 10.1002/pro.244

Figure 2.

Figure 2

Chemical structures of stimulants and the amino acid sequence of scFv6H4. (A) Chemical structure of related stimulants (+)-amphetamine, (+)-methamphetamine, (+)-3,4-methylenedioxymethamphetamine, and hapten (+)-METH-P6, that was used to generate the parent mAb6H4. (B) The amino acid sequence of scFv6H4 with Kabat numbering.12 The framework and CDR loop regions are indicated above the sequence. Residues forming the aromatic barel around METH and MDMA are boxed in bold. Residues that form salt bridge or hydrogen bond are boxed in bold and shaded.