Table I.

The 20 Homodimers with the Highest Percentage of Monomer Surface Area Involved in the Dimerization Surface in the Set of Nonredundant PDB Structures

Rank	PDB ID	Interface surface area (Å2)	Percent total surface area (%)	Protein	Organism
1	1W5U	1490	47.0	Gramicidin D	Bacillus brevis
2	1U42	4583	45.9	Mutant of dimerization domain of NF-kB p50 factor	Mus musculus
3	1W7R	1165	44.4	Feglymycin	Streptomyces
4	2RH0	6167	43.3	NudC domain-containing protein 2	Mus musculus
5	1ZK9	5436	43.1	Dimerization domain of NF-kB RelB	Mus musculus
6	3DIE	4290	42.0	Thioredoxin W28A mutant	Staphylococcus aureus
7	3FJ5	2814	42.0	C-src-SH3 domain	Gallus gallus
8	2B1Y	5499	41.6	ATU1913	Agrobacterium tumefaciens str. C58
9	2I8D	4850	41.2	COG5646	Lactobacillus casei
10	2FDO	3960	41.1	AF2331	Archaeoglobus fulgidus DSM 4304
11	1G8E	3302	40.9	Flagellar transcriptional regulator FlhD	Escherichia coli
12	2DLB	3270	40.6	YopT	Bacillus subtilis
13	2OPL	6110	40.1	OsmC-like protein	Geobacter sulfurreducens
14	1WKQ	4129	39.8	Guanidine deaminase	Bacillus subtilis
15	1MYK	1786	39.5	Arc repressor mutant PL8	Enterobacteria phage p22
16	1K9U	2542	39.2	Pollen allergen Phl p 7	Phleum pratense
17	2OTA	2768	39.1	UPF0352 protein CPS_2611	Colwellia psycherythraea 34h
18	3GXZ	4373	39.0	Cyanovirin-n	Nostoc ellipsosporum
19	2RFP	5999	38.7	Putative NTP pyrophosphohydrolase	Exiguobacterium sibiricum
20	1WZ3	3570	38.7	Plant ATG12	Arabdopsis thaliana