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. Author manuscript; available in PMC: 2009 Dec 3.
Published in final edited form as: J Magn Reson. 2007 Jun 10;187(2):320–326. doi: 10.1016/j.jmr.2007.06.001

Figure 1.

Figure 1

NMR pulse sequence for the generation of 2D NMR spectra through indirect detection of intra-molecular zero-quantum-coherences from 3D spatially localized volumes. t1 and t2 correspond to the indirect and direct detection periods, whereas TE1 and TE2 are optimized to provide the highest signal recovery for a given scalar-coupled spin-system. The phase of the 45° mixing pulse is cycled (+y, −y) in concert with the receiver phase (+x, −x) in order to eliminate unwanted signals created by T1 recovery during the t1 period.