Table 1.
Description of the studies included in the meta-analysis of the relationship of MTHFR C677T and HCC
| Author | Year | Country | Case/control | Source of controls | Cases | controls | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| CC | CT | TT | CC | CT | TT | |||||
| Fabris | 2009 | Italy | 65/236 | Population and hospital | 22 | 30 | 13 | 111 | 195 | 77 |
| DÁmico | 2009 | Italy | 94/308 | Population and hospital | 30 | 37 | 27 | 133 | 131 | 44 |
| Kwak | 2008 | Korea | 96/201 | population | 32 | 46 | 18 | 64 | 106 | 31 |
| Yuan | 2007 | American | 118/209 | population | 53 | 51 | 14 | 80 | 99 | 30 |
| Yuan | 2007 | China | 247/248 | hospital | 159 | 71 | 17 | 156 | 74 | 18 |
| Mu | 2007 | China | 194/391 | population | 50 | 114 | 30 | 135 | 199 | 57 |
| Zhu | 2006 | China | 508/543 | hospital | 172 | 226 | 110 | 173 | 268 | 102 |
| Ventura | 2005 | Italy | 22/162 | Population and hospital | 8 | 5 | 9 | 94 | 48 | 20 |
| Yang | 2005 | China | 322/185 | population | 229 | 80 | 13 | 131 | 46 | 8 |
| Saffroy | 2004 | France | 148/232 | Population and hospital | 67 | 69 | 12 | 92 | 114 | 26 |