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. Author manuscript; available in PMC: 2009 Dec 3.
Published in final edited form as: J Allergy Clin Immunol. 2009 Jul 9;124(3):558–565.e3. doi: 10.1016/j.jaci.2009.04.035

FIG 5.

FIG 5

Effect of sPLA2 and cPLA2 inhibitors on LTC4 production from anti-IgE–stimulated HLMCs. The cells were preincubated (for 15 minutes at 37°C) with increasing concentrations of Me-Indoxam or AZ-1 before stimulation (for 30 minutes at 37°C) with anti-IgE (1 μg/mL). LTC4 production was determined in supernatants by using an enzyme immunoassay. Inhibition of LTC4 production was expressed as a percentage of maximum response. Data are presented as means ± SEs of 4 experiments. *P < .05 versus anti-IgE; **P < .01 versus anti-IgE.