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. 2009 Nov 16;5:921–936. doi: 10.2147/vhrm.s5551

Figure 3.

Figure 3

Metabolic pathway of pitavastatin. Adapted with permission from Fujino H, Yamada I, Shimada S, et al. Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization. Xenobiotica. 2003;33(1):27–41;37 Fujino H, Saito T, Tsunenari Y, et al. Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors. Xenobiotica. 2004;34(11–12):961–971.38 Copyright © 2003, 2004 Taylor & Francis.

Abbreviation: Glu-, monoglucuronic acid conjugate.