TABLE 3.

Step 2 Median (Range) Fasting Serum Lipid Values (mg/dL) on Combined Fenofibrate and Fish Oil

	Step 2 Entry	Week 18	Absolute Change	P*	Percent Change	P*
Combined group overall (n = 67)
TG	377 (205 to 1476)	279 (97 to 1458)	−108 (−788 to 871)	<0.001	−30% (−78 to 231)	<0.001
LDL-C	106 (60 to 214)	120 (49 to 216)	13 (−64 to 102)	0.002	13% (−45 to 117)	0.001
HDL-C	32 (7 to 53)	33 (16 to 63)	2 (−13 to 27)	0.019	6% (−27 to 129)	0.019
TC	237 (128 to 355)	220 (133 to 370)	−5 (−87 to 59)	0.091	−2% (−33 to 27)	0.135
Non-HDL-C	207 (100 to 314)	184 (98 to 318)	−6 (−90 to 54)	0.034	−4% (−38 to 23)	0.054
Fish oil initiated first in step 1, adding fenofibrate at week 10 (n = 36)
TG	369.5 (205 to 1278)	280 (97 to 1458)	−92 (−616 to 871)	<0.001	−28% (−71 to 231)	<0.001
LDL-C	101 (60 to 214)	119.5 (49 to 216)	11.5 (−64 to 102)	0.131	11% (−45 to 117)	0.026
HDL-C	30.5 (22 to 51)	32.5 (21 to 63)	2 (−8 to 27)	0.057	8% (−25 to 75)	0.032
TC	241 (128 to 355)	219.5 (133 to 342)	−3 (−75 to 50)	0.247	−1% (−27 to 27)	0.314
Non-HDL-C	211.5 (100 to 307)	183 (102 to 318)	−7 (−69 to 49)	0.081	−4% (−32 to 23)	0.110
Fenofibrate initiated first in step 1, adding fish oil at week 10 (n = 31)
TG	414 (206 to 1476)	279 (105 to 970)	−117 (−788 to 176)	<0.001	−36% (−78 to 49)	<0.001
LDL-C	116 (70 to 191)	120 (69 to 203)	13 (−29 to 61)	0.003	13% (−26 to 76)	0.004
HDL-C	33 (7 to 53)	34 (16 to 58)	1 (−13 to 10)	0.170	3% (−27 to 129)	0.262
TC	231 (166 to 321)	222 (137 to 370)	−5 (−87 to 59)	0.239	−2% (233 to 19)	0.297
Non-HDL-C	199 (136 to 314)	186 (98 to 312)	−5 (−90 to 54)	0.236	−3% (−38 to 21)	0.302

^*Signed rank test.

TC indicates total cholesterol.