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. Author manuscript; available in PMC: 2010 Dec 29.
Published in final edited form as: Brain Res. 2009 Sep 23;1305:47–63. doi: 10.1016/j.brainres.2009.09.065

Figure 2.

Figure 2

Early life experience and social defeat during adulthood interact to alter slc6a4 mRNA expression in adult midbrain serotonergic neurons. A) Mean slc6a4 mRNA expression levels in MS15, AFR, and MS180 rats, regardless of adult experience, based on the mean expression levels in forty-eight subdivisions of the DR. B) Mean slc6a4 mRNA expression levels in adult rats exposed to a novel cage (control condition) or social defeat, regardless of early life experience, based on the mean expression levels in forty-eight subdivisions of the DR. C) Mean slc6a4 mRNA expression levels in MS15, AFR, and MS180 rats exposed to a novel cage control condition (control, left) or social defeat (right) as adults. Slc6a4 mRNA expression was measured 4 h following exposure to a novel cage control condition or to social defeat. **P < 0.01, comparison of MS15 and MS180 groups. bP < 0.01, comparison of AFR and MS180 groups. Data are illustrated as means + SEM.