Fig. 6.

Time course of cold sensitivity. The frequencies of the foot withdrawals to cold stimuli caused by the application of acetone to the hindpaw are depicted. Before surgery, the withdrawal frequencies were 13.9 ± 2.7% in the 6.25 mm group and the 12.6 ± 3.2% in 12.5 mm group. Two weeks after the SCI, the withdrawal frequencies to the application of acetone in the 6.25- and 12.5 mm groups increased to 35.7 ± 4.6% and 32.1 ± 5.4%, respectively. The withdrawal responses in the 12.5 mm group were generally higher than those in the 6.25 mm, however, there was no difference between the two experimental groups. The asterisks (*) indicate the values significantly different from the pre-operative value. The time after the spinal cord contusion indicates weeks (W) following the spinal contusion, except for "pre", which represents the preoperative test period.