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. Author manuscript; available in PMC: 2010 Dec 10.
Published in final edited form as: J Med Chem. 2009 Dec 10;52(23):7678–7688. doi: 10.1021/jm900694z

Figure 2.

Figure 2

Primary liver tumor xenograft growth inhibition and mouse survival as a function of i.v. dose of PPD with 10 NOD/SCID mice per group. Treatment started 7 days after implantation of N-Hep G2 liver cancer cells in mice (left flank). Doses are in mg/kg of doxorubicin equivalent weight. Drug delivery vehicle was 5% DMSO/95% D5W. Control mice received drug delivery vehicle. All 50 mice developed tumors. Mice were treated on days 7, 14, and 21; mice in 3 mg/kg PPD group were redosed at 5 mg/kg on days 45 and 52. Error bars represent one standard deviation.