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Effects of integrin α5β1 antagonist on hfRPE migration. A. Integrin α5β1 antagonist JSM6427 (100 μM, 400 μM) completely abolished the stimulatory effect of 5% serum induced hfRPE migration (uncoated plate). B. JSM6427 (50 μM) significantly inhibited bFGF and PDGF-BB induced hfRPE migration on fibronectin coated plates. * P<0.05, compared to SFM control. # P<0.05
