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. Author manuscript; available in PMC: 2010 Dec 10.
Published in final edited form as: J Med Chem. 2009 Dec 10;52(23):7380–7388. doi: 10.1021/jm900256f

Table 1.

Table of IC50 values (μM) for Growth Inhibition and Gene Regulation in LNCaP cells for 28-33; data is shown in Figure 5. IC50 for gene regulation was measured only for 28, 31 and 33. For 28, 31 and 33, the (IC50 for Growth Inhibition)/(IC50 for Gene Regulation) ratio was calculated.

Compound Growth Inhibition IC50 (μM) Gene Regulation IC50 (μM) Growth Inhibition IC50 (μM)/Gene Regulation IC50 (μM)
28 > 30 6.0 (± 2.6) ≥ 5
29 > 30 ------ ------
30 > 30 ------ ------
31 1.7 (± 0.3) 0.3 (± 0.1) 6.1
32 0.6 (± 0.1) ------ ------
33 0.4 (± 0.0) 0.6 (± 0.3) 0.7