Table 3.
Follicle number, oocyte number, follicle:oocyte ratio, maturation rate and fertilization rate in each of the three genotypes for PvuII, XbaI and TA dinucleotide polymorphisms
| Genotypes of ESR1, PvuII | Genotypes of ESR1, XbaI | Genotypes of ESR1,(TA)n repeat | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PP (n = 28) | Pp (n = 50) | pp (n = 26) | p value | XX (n = 36) | Xx (n = 50) | xx (n = 18) | p value | SS (n = 35) | SL (n = 50) | LL (n = 19) | p value | |
| # of follicles Median(Min-max)% | 18.5 (15.25–23.00) | 19.0 (15.00–23.25) | 19.0 (16.00–25.00) | 0.579a | 18.5 (16.00–23.75) | 19.0 (15.00–24.00) | 19.0 (16.00–23.25) | 0.972a | 18.0 (15.00–24.00) | 19.5 (16.00–23.00) | 19.0 (15.00–24.00) | 0.894a |
| # of collected oocyte Median(Min-max)% | 18.5 (14.00–22.00) | 17.5 (15.00–22.25) | 19.0 (15.00–22.25) | 0.812a | 18.0 (15.00–22.00) | 17.5 (15.00–23.00) | 18.5 (15.00–22.00) | 0.938a | 17.0 (14.00–23.00) | 18.0 (16.00–22.25) | 19.0 (14.00–22.00) | 0.836a |
| Maturation rate Median(Min-max)% | 94.0 (87.09–100.0)b | 93.5 (86.76–96.03)c | 82.0 (63.38–89.83)b,c | p < 0.001a | 94.3 (87.84–100.00)d | 91.7 (80.75–95.50)e | 86.5 (65.00–91.39)d,e | p < 0.001a | 92.9 (83.33–95.55) | 92.5 (85.80–95.59) | 86.4 (66.67–92.86) | 0.075a |
| Fertilization rate Median(Min-max)% | 86.6 (72.1–94.02)b,f | 71.0 (59.58–81.25)f | 60.0 (48.86–75.48)b | p < 0.001a | 84.0 (72.61–94.36)d,g | 68.8 (59.58–78.33)g | 59.5 (39.78–79.56)d | p < 0.001a | 80.0 (70.0–92.85)h,j | 71.1 (60.0–81.53)i,j | 58.8 (40.00–71.43)h,i,j | p < 0.001a |
| # of grade 1–2 embryos Median (Min-max)% | 10.0b (6.00–14.00) | 9.5c (4.00–16.00) | 8.0b,c (4.00–12.00) | p < 0.001 | 9.0 (4.50–17.00) | 10.0 (6.00–14.00) | 8.5 (3.50–14.00) | 0.668 | 10.0 (7.00–12.00) | 12.0 (6.00–17.00) | 10.0 (5.00–14.00) | 0.772 |
| # of grade 3–4 embryos Median(Min-max)% | 6.0b (3.00–10.00) | 7.0c (2.00–10.00) | 7.5b,c (3.00–11.00) | p < 0.001 | 7.0 (2.00–11.00) | 8.0 (2.00–7.00) | 8.0 (3.0–15.00) | 0.645 | 6.5 (3.00–10.00) | 5.5 (2.00–11.00) | 6.0 (2.00–12.00) | 0.739 |
| Frequency (%) of clinical pregnancies | 35.7 | 34.0 | 30.8 | 0.556k | 33.3 | 36.0 | 27.8 | 0.895k | 31.4 | 36.0 | 31.5 | 0.712k |
aKruskal Wallis test
bSignificant relationship was found between the groups when PP and pp genotypes were compared p < 0.001
cSignificant relationship was found between the groups when Pp and pp genotypes were compared p < 0.001
fSignificant relationship was found between the groups when PP and Pp genotypes were compared p < 0.001
dSignificant relationship was found between the groups when XX and xx genotypes were compared p < 0.001
eSignificant relationship was found between the groups when Xx and xx genotypes were compared p = 0.028
gSignificant relationship was found between the groups when XX and Xx genotypes were compared p < 0.001
hSignificant relationship was found between the groups when SS and LL genotypes were compared p < 0.001
iSignificant relationship was found between the groups when SS and SL genotypes were compared p = 0.011
jSignificant relationship was found between the groups when SL and LL genotypes were compared p = 0.013
kLogistic regression analysis