Table 1.
Cases (n=35) | Controls (n=54) | |
---|---|---|
Clinical presentation | ||
-Pulmonary tuberculosis | 35 | 0 |
-Lobar community acquired pneumonia | 0 | 37 |
-Acute exacerbation in COPD * | 0 | 8 |
-Nosocomial pneumonia | 0 | 4 |
-Interstitial community acquired pneumonia # | 0 | 4 |
-Empyema | 0 | 1 |
-Pleuropericarditis | 0 | 1 |
Systemic disease | ||
-HIV | 9 | 7 |
-Vasculitis | 0 | 1 |
-Collagen disease | 0 | 1 |
-Steroid therapy | 1 | 2 |
-Diabetes | 1 | 3 |
Clinical picture | ||
-Acute (< 2 weeks) | 9 | 26 |
-Sub-acute | 32 | 22 |
Pulmonary infiltrate | ||
-Alveolar | 20 | 32 |
-Interstitial | 1 | 11 |
-Pleural effusion | 4 | 8 |
-No infiltrate | 1 | 12 |
Basal Ca-125 level (IU/ml) | ||
-Mean (± DE) | 104.9 (± 136.1) | 27.1 (± 19.7) |
-Median | 46 | 24 |
-Range | 10-500 | 5-123 |
Ca-125 level during therapy (2-4 month (IU/ml) | ||
-Mean (± DE) | 59.5 (± 88.5) | |
-Median | 31 | |
-Range | 13-63 |
COPD: chronic obstructive pulmonary disease.
All three patients responded to clarithromycin and a probable atypical pneumonia diagnosis was established.