Table 1. Binding of four HIV-1 isolates to erythrocytes derived from 30 different donors.
Donor no. | ABO blood type | Rh | Duffy blood type | Virus isolate | Viral clade/co-receptor | p24 added (pg) | No. of erythrocytes added | % of p24 bound to cellsa |
Q1 | AB | + | 99KE_KNH1135 | A/R5 | 5,999 | 5×107 | 4.24b | |
Q2 | A | + | 89BZ_167 | B/R4 | 30,257 | 5×108 | 3.48c | |
Q3 | B | + | 89BZ_167 | B/R4 | 30,257 | 5×108 | 1.09 | |
Q4 | O | + | 89BZ_167 | B/R4 | 12,053 | 5×108 | 1.06 | |
Q5 | O | + | Fy(a+b-) | 89BZ_167 | B/R4 | 30,257 | 5×108 | 2.30d |
91US_4 | B/R5 | 77,236 | 5×108 | 0.03 | ||||
99KE_KNH1135 | A/R5 | 29,995 | 5×108 | 0.61 | ||||
Q6 | O | + | Fy(a+b+) | 99KE_KNH1135 | A/R5 | 29,995 | 5×108 | 0.53 |
91US_4 | B/R5 | 77,236 | 5×108 | 0.28 | ||||
90US_873 | B/R5 | 8,486 | 2×108 | 3.77 | ||||
89BZ_167 | B/R4 | 30,257 | 5×108 | 2.66b | ||||
Q7 | O | + | Fy(a+b+) | 99KE_KNH1135 | A/R5 | 29,995 | 5×108 | 1.23 |
91US_4 | B/R5 | 77,236 | 5×108 | 0.66 | ||||
Q8 | O | − | Fy(a+b−) | 91US_4 | B/R5 | 77,236 | 5×108 | 0.36 |
99KE_KNH1135 | A/R5 | 29,995 | 5×108 | 1.41 | ||||
90US_873 | B/R5 | 8,486 | 2×108 | 3.65 | ||||
Q9 | A | + | Fy(a−b−) | 90US_873 | B/R5 | 8,486 | 5×108 | 1.35 |
99KE_KNH1135 | A/R5 | 29,995 | 5×108 | 0.88 | ||||
91US_4 | B/R5 | 77,236 | 5×108 | 0.18 | ||||
89BZ_167 | B/R4 | 30,257 | 5×108 | 2.99 | ||||
R1 | O | − | 89BZ_167 | B/R4 | 30,257 | 5×108 | 5.61 | |
R2 | A | + | 89BZ_167 | B/R4 | 15,129 | 5×108 | 2.49b | |
R3 | O | − | 89BZ_167 | B/R4 | 45,386 | 7.5×108 | 4.47b | |
R4 | O | + | 89BZ_167 | B/R4 | 30,257 | 5×108 | 2.91 | |
R5 | O | + | 89BZ_167 | B/R4 | 30,257 | 5×108 | 4.37 | |
R6 | O | + | 89BZ_167 | B/R4 | 30,257 | 5×108 | 1.84 | |
R7 | A | + | 89BZ_167 | B/R4 | 30,257 | 5×108 | 6.02 | |
R8 | O | + | 89BZ_167 | B/R4 | 30,257 | 5×108 | 5.67 | |
R9 | O | + | 89BZ_167 | B/R4 | 7,564 | 2.5×108 | 1.07 | |
S1 | A | + | 89BZ_167 | B/R4 | 15,129 | 5×108 | 1.59 | |
S2 | O | + | 89BZ_167 | B/R4 | 45,386 | 7.5×108 | 0.69 | |
S3 | A | − | 89BZ_167 | B/R4 | 30,257 | 5×108 | 3.27 | |
S4 | O | + | 89BZ_167 | B/R4 | 15,129 | 5×108 | 5.40 | |
S5 | O | + | 89BZ_167 | B/R4 | 72,320 | 3×109 | 0.56 | |
S6 | A | + | 89BZ_167 | B/R4 | 15,129 | 5×108 | 4.40 | |
S7 | A | + | 89BZ_167 | B/R4 | 15,129 | 5×108 | 5.55 | |
S8 | O | + | 89BZ_167 | B/R4 | 7,564 | 5×108 | 0.75 | |
S9 | B | + | 89BZ_167 | B/R4 | 7,564 | 5×108 | 0.49 | |
T1 | O | + | 89BZ_167 | B/R4 | 72,320 | 3×109 | 1.65 | |
T2 | A | + | 89BZ_167 | B/R4 | 72,320 | 3×109 | 3.00 | |
T3 | A | + | 89BZ_167 | B/R4 | 72,320 | 3×109 | 0.67 | |
Mean | 2.32 | |||||||
SD | 1.82 | |||||||
Median | 1.65 | |||||||
Range | 0.03–6.02 |
Values are from a single experiment except for means of btwo, cfour or dfive experiments.