LY341495 attenuates lateral olfactory tract (LOT)-evoked optical signals. Each panel depicts the amplitude of optical responses, recorded by each of the 464 photodiodes. Signal amplitudes, expressed as a percentage above mean baseline values, are color-coded; color scale at top applies to all images. Time intervals beneath the images are relative to the onset of LOT stimulation. Single shocks applied to the LOT-elicited responses that were first observed in the external plexiform layer. LOT-evoked responses then spread sequentially into the superficial GC layer (GCL). Application of LY341495 (100 μM) reduced the amplitude of LOT-evoked voltage-sensitive dye optical signals. Gl, glomerular layer; epl, external plexiform layer; mcl, mitral cell layer.