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. 2009 Nov 20;9:134. doi: 10.1186/1471-2229-9-134

Table 7.

Analysis of loops C and D in MIPs from different organism groups

MIP Subfamily No. of sequences Length of the loop C Loops with ≥ 3 Gly Length of loop D No. of basic residues in loop D
Dicot XIP1s 18 33 All dicot, XIPs 15 -- 16 ≥ 3 (19 out of 22)
Dicot XIP2s 4 25

Moss XIPs 3 31 -- 34 All 12-16 1 (2 out of 3)

Fungi XIPs 9 20 -- 23 All 16 2 (8 out of 9)

All PIPs 54 21 -- 22 53 out of 54 13 -- 14 4 (53 out of 54)

All TIPs 49 17 40 out of 49 9 -- 11 2 (41 out of 49)

All NIPs 37 16 -- 24 12 out of 37 8 -- 9 1 (32 out of 37)

All SIPs 14 14-19 None 8 -- 9 2 (10 out of 14)

Human glycerol transporting AQPsa 4 35 All 10 0 (2 out of 4)
2 (2 out of 4)

Other Human AQPsb 9 20-23 AQP1, AQP4 5 -- 9 2 basic (7 out of 9)

aAQP3, AQP7, AQP9, AQP10 are the human AQP homologs that transport glycerol.

bAQP0, AQP1, AQP2, AQP4, AQP5, AQP6, AQP8, AQP11, AQP12