Table 5.
Changes of mean TGF-β1 ratio during the course of radiation therapy
Mean of Ratio ± SD | ||||
---|---|---|---|---|
Time | RP | Non-RP | p value* | |
RP2 | Before RT | |||
(n = 8) | Beginning of RT | 0.8 ± 0.2 | 1.0 ± 0.2 | 0.019 |
Middle of RT | 0.8 ± 0.4 | 0.9 ± 0.4 | 0.238 | |
End of RT | 0.8 ± 0.2 | 0.9 ± 0.3 | 0.346 | |
2 wks after RT | 1.0 ± 0.6 | 0.9 ± 0.3 | 0.576 | |
4 wks after RT | 1.6 ± 1.0 | 0.8 ± 0.3 | 0.081 |
Abbreviations: RT, radiation therapy; wks, weeks; RP2, development of grade ≥ 2 radiation pneumonitis
* student's t-test