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Crystal structure of TbTryR. Panel A, the crystal structure is coloured to differentiate the two subunits forming the homodimer. FAD is shown in red and NADPH in blue. Panel B, a close-up of the TbTryR active site (purple and yellow) superimposed onto the TcTryR active site (black and grey, pdb code 1BZN ). Trypanothione is shown bound into the active site of the TcTryR structure.
