Fig. 4.

Resolution of thermal sensory abnormalities with DBS. (A) QST of affected left side (medial shin, volar forearm and maxilla) before and after DBS Showed the presence of cold and warm hypoaesthesia and cold hypoalgesia. After PVG DBS there was a significant improvement in the cold detection and cold pain thresholds with a trend also seen towards normalisation of the warm detection threshold. (B) Comparison of the left and right upper limbs before and after DBS. The significant side-to-side differences in thermal detection and cold pain thresholds were resolved by PVG DBS (repeated measures ANOVA with Bonferoni post tests ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001).